Readers ask: What Is The Role Of Exogenous Insulin Therapy In Patients With Type 2 Diabetes?

How does exogenous insulin work in type 2 diabetes?

Exogenous insulin is injected and acts similarly to its endogenous counterpart, helping to normalize glucose levels and metabolism. Insulin works mechanistically by activating glucose transporters in the cell membrane to cause uptake of glucose into the cell.

What is the role of insulin in type 2 diabetes?

Insulin is needed to move blood sugar (glucose) into cells. Inside the cells, glucose is stored and later used for energy. When you have type 2 diabetes, your fat, liver, and muscle cells do not respond correctly to insulin. This is called insulin resistance.

What is the role of insulin injections in the treatment of type I and type II diabetes?

Human insulin is used to control blood sugar in people who have type 1 diabetes (condition in which the body does not make insulin and therefore cannot control the amount of sugar in the blood) or in people who have type 2 diabetes (condition in which the blood sugar is too high because the body does not produce or use

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When should insulin therapy be considered in a person with type 2 diabetes?

Insulin should be initiated when A1C is ≥7.0% after 2–3 months of dual oral therapy. The preferred regimen for insulin initiation in type 2 diabetes is once-daily basal insulin. In addition to timely initiation, rapid titration of the dose is indispensable for successful insulin therapy.

What is the most common side effect of insulin?

Common side effects include: initial weight gain as the cells start to take in glucose. blood sugar that drops too low, or hypoglycemia. rashes, bumps, or swelling at an injection site.

How do you determine insulin resistance?

Insulin resistance is when cells in your muscles, fat, and liver don’t respond well to insulin and can’t use glucose from your blood for energy. To make up for it, your pancreas makes more insulin. Over time, your blood sugar levels go up.

Which insulin is best for type 2 diabetes?

Hypoglycemia risk is very low among type 2 diabetic patients just starting insulin therapy, making NPH insulin the most cost-effective drug.

Is insulin the best treatment for diabetes?

For most people with diabetes, insulin is the most reliable way to lower blood sugar. But is insulin the best way to prevent death and heart disease in Type 2 diabetes? Recent studies seem to show that people with Type 2 treated with certain oral medications had less risk of dying than did people taking insulin.

Can too much insulin raise blood sugar?

Excess insulin in the bloodstream causes cells in your body to absorb too much glucose (sugar) from your blood. It also causes the liver to release less glucose. These two effects together create dangerously low glucose levels in your blood.

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Is insulin better or medicine?

If pills aren’t enough to get your blood sugar under control, your doctor may recommend insulin. You take insulin as a shot. You can’t take it like a pill because normal digestion would destroy it. There are several different types, and they all work in different ways.

Which type of diabetes requires insulin injections?

People who have type 1 diabetes must take insulin as part of their treatment. Because their bodies can’t make insulin anymore, they need to get the right amount to keep their blood sugar levels in a healthy range. The only way to get insulin into the body now is by injection with a needle or with an insulin pump.

Which type of diabetes is worse?

Type 2 diabetes accounts for the vast majority of people who have diabetes—90 to 95 out of 100 people. In type 2 diabetes, the body isn’t able to use insulin the right way. This is called insulin resistance. As type 2 diabetes gets worse, the pancreas may make less and less insulin.

Do you have to inject insulin with type 2 diabetes?

Taking insulin helps you manage your blood sugar levels. Everybody with type 1 and some people with type 2 diabetes need to use insulin as a treatment. You take insulin by injecting it using an insulin pen, or by using an insulin pump. Pumps aren’t available to everyone – only for people who have type 1 diabetes.

Where should you not inject insulin?

DON’T: Inject insulin just anywhere. Insulin should be injected into the fat just underneath the skin rather than into muscle, which can lead to quicker insulin action and greater risk of low blood sugar. The stomach, thighs, buttocks, and upper arms are common injection sites because of their higher fat content.

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What happens if insulin is taken after food?

Mealtime insulin also comes with other risks. If you take your mealtime insulin, but are unable to eat, you could become hypoglycemic. Hypoglycemia occurs when your blood sugar levels get too low. This can be very dangerous.

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